ABSTRACT
Background: Hospitalization is not normally necessary in all COVID patients, nor is lab tests and PCR. There is subjective evidence that patients with "slight" COVID-19 may complain of persistent symptoms weeks after the infection. Methods: A group of 489 patients was tracked for 8 months after recovering from mild to severe COVID-19 infection at a Saudi tertiary hospital between March 6th and December 2nd 2021, IRB and informed permission acquired #89742/2022, and participation was freely. We evaluated the clinical condition, lab findings, and demographic features of the patients and used SPSSversion26 to perform our statistical analysis. Results: All of them were followed up until the second follow-up visit at 4.3 months (median 131 days (IQR 112-149). Age was a significant indicator of post CL syndrome, obtained p-value for age, 0.032, was less than critical alpha level of 0.05. BMI was a significant indicator of post CL syndrome, obtained p-value 0.032 (odds ratio (OR) 1.04;95% confidence interval (95% CI): (1.00 - 1.073)), body aches was a significant indicator of post CL syndrome, obtained p-value 0.040 (OR 0.59;95% CI (0.36-0.98)), fatigue was a significant indicator of post CL syndrome, obtained p-value.005 (OR 2.05;95% CI (0.99-4.22)). Conclusion: Manifold signs are present around 3 months after the onset of signs in formerly hospitalized and non-hospitalized participants with established or suspected COVID-19. This suggests the presence of a "(post-COVID-19 syndrome)" and peaks the final healthcare needs in a subset of individuals with "slight" or "Spartan" COVID-19.
ABSTRACT
Background: Early and accurate detection of respiratory viruses (RV) is important for patient management. We have previously shown that self-collected nasal swabs (NS) are feasible and as sensitive as clinician-collected nasal washes for detection of RV, but the additive benefit of self-collected throat swabs is unknown. Objectives: To test the rise in auto sufficient nasal yields to the throat swabs in patients with upper respiratory (URTI) symptoms for PCR identification of RV. Study Design: Patients with URTI symptoms self-collected paired polyurethane foam NS and nylon flocked throat swabs and completed a symptom survey. Swabs were tested for 12 RV by real-time reverse transcription (RT)-PCR. Descriptive, McNemar's, and Wilcoxon signed rank statistical tests were used. Results: The sample was made up of 115 paired swab nasals and throat, with at least 1 specimen being positive for RV (71/115 (62 percent), including 51 positive for both specimens, 17 positive for NS only and 3 favorable for RV only with throat swab. NS was 96 percent sensitive (95 percent CI: 88-99) compared with 76 per cent in throat swabs, p<0.001 (95 percent CI: 65-85). The median PCR period threshold (Ct) of 51 concordant samples was lower in NS (25.1) than in swabs of the throat (32.0). Conclusion: Self-collection of NS was significantly more sensitive than self-collection of throat swabs for detection of RV by RT-PCR. The addition of throat sampling does not appear to increase the diagnostic load in the self-testing setting. © 2018, EBX. All rights reserved.
ABSTRACT
Background & aims: Riyadh, Saudi Arabia latest center for the 2019 pandemic of Coronavirus (COVID-19). The ethnic populations with a higher incidence of obesity tend to be particularly impacted. Our aims were to evaluate the characteristics and early effects on Orthopedic Patients with COVID-19, and to evaluate Orthopedic Patients with poorer outcomes regardless of age, sex and other comorbidities. Methods: The first 200 Orthopedic Patients admitted to a tertiary medical center with COVID-19 were included. At least three weeks after admission, electronic patient reports were analyzed. Mortality in hospitals was the main endpoint. Results: 200 Orthopedic Patients (female sex: 102) were included. The average BMI was 30 kg / m2. The middle age was 64. The three most prevalent comorbidities were hypertension (76 percent), hyperlipidemia (46.2 percent), and diabetes (39.5 percent). A multi-variate study reveals that BMIs was indigenously correlated with a higher in patient mortality of 35 kg / m2 (reference: BMI 25-34 kg / m2;OR: 3.78;95 percent CI: 1.45-9.63;p = 0.006;p = 0.061) and age rises (analyzed in quartiles;OR: 1.73;95 percent CI: 1.13-2.63;p = 0.011). Conclusions: This cohort of hospitalized Orthopedic Patients with COVID-19 in the majority minority group is individually related to greater in-hospital mortality and overall poorer in-hospital results with extreme obesity, rising age and male sex.
ABSTRACT
Diabetes is a challenging clinical problem facing obstetricians and gynecologists when it comes to in vitro fertilization and embryo transfer (IVF-ET). During the COVID-19 pandemic we are living nowadays, COVID-19 becomes a new superimposing challenge for diabetic females need IVF-ET procedures. The persistent lock-down of diabetic health facilities already advised by numerous organizations and contributing to challenging diabetes treatment is harmful to the whole population and in particular to patients with infertilities. Around 0.3% of all babies born last year were conceived with IVF-ET therapies worldwide. We recommend remedies to foresee more delicate infertility cases so as to prepare for a resumption of temporarily suspended fertility treatment.. In an age of crucial challenges for our national health services, complication prevention and tension management can help competent agencies and health providers identify patients that should be preferred to begin fertility treatment in a healthy environment. What we consider as a possible possibility is the gradual restart of IVF, which needs many measures for diabetic patients. The problem of restarting IVF installations after the current lockdown is real since each nation follows a certain recovery curve. Especially as a result of silent dissemination, attention should be provided to COVID-19 infection among patients and health-care staff after the restart of IVF therapy. (Clin Diabetol 2020;9;6: 372–377) © 2020 Via Medica. All rights reserved.
ABSTRACT
Background: Saudi Arabia is one of the nations impacted by the epidemic of COVID-19. Objectives: To address psycho-behavioral problems to the pandemic of COVID-19 in the whole population of Saudi Arabia, namely: 1) obstacles to infection control measures against COVID infections;2) adverse responses to COVID-19;and 3) fear among the general population in Saudi Arabia. Methods: An electronic population based cross sectional survey using a validated electronic questionnaire was performed between 23 July and 1 August 2020. Among the whole estimated target population of COVID-19 patients in Saudi Arabia. Using multi-stage random sampling technique all over the governorates. The six-item variant of the State-Trait-Anxiety-Stock (STAS-6) was used to measure rates of anxiety. Estimated target population of 67,000 Covid-19 patients according to last national report of MOH. A multi stage sampling from different affected governorates. Sample size was calculated using Steven Sampthon formula to be 2230 patient. Sample was collected from MOH electronic registries approved by the ethical committee of KSUMC # (78/82/KSUMC/IRB-COVID-3792). Results: A total of 1,800 full replies have been received. Almost 60 percent reported having trouble wearing a face mask to guard against COVID infection. The mean and standard deviation (SD) for the overall avoidance obstacle value was 35.8 (SD +/- 7.1;scale 18 to 68) out of a maximum 72. Male respondents [odds ratio (OR) = 1.25;95 % confidence interval (CI) 1.03 to 1.51] and many respondents who regarded their health condition as poor / fair (OR = 1.49;95 % CI 1.31 to 1.82) were indicators of Strong obstacles to avoidance. Negative feelings such as anxiety (74.6%), accompanied by sadness (43.4%) and stigma (23.0%) correlated with SARS-CoV-2 infection has been identified. The addressing groups that their wellbeing was viewed as poor / fair (OR = 2.19;95 % CI 1.57 to 3.04) and a higher risk was recorded to get more depressive feelings. Anxiety rating results showed 68.0 per cent (95 per cent CI 65.8 to 65.8 per cent). (70.1) mild to extreme anxiety recorded. Participants who see their well-being as poor / fair (OR = 3.46;95% CI 12.22 to 5.40) and who were female (OR = 1.91;95 % CI 1.55 to 2.36) were female;predictors with mild to extreme fear. Conclusion: Psycho behavioral measures are expected to promote the management and monitoring of the epidemic of COVID-19.
ABSTRACT
In December 2019, a new coronavirus, now labeled as severe acute respiratory syndrome coronavirus 2, induced an episode of acute atypical respiratory illness started in Wuhan, Province of Hubei, China. The illness triggered by this virus was called coronavirus disease-19 (COVID-19). The infection is spread within humans and has triggered a global pandemic. The amount of death tolls continues to increase and a growing number of countries have been driven to create social barriers and lock-ups. The shortage of tailored counseling remains an issue. Epidemiological researches have shown that elderly patients are more vulnerable to serious diseases, while children tend to have milder symptoms. Here, we checked the latest understanding of this disease and found a possible explanation of the potential sequel and the expectations for the future.